Hyperpigmentation
Hyperpigmentation


Hyperpigmentation refers to a common dermatological condition characterised by patches of skin that become darker in colour than the surrounding area due to excess production of melanin, the pigment responsible for skin coloration. This condition can result from various factors such as sun exposure, hormonal changes, inflammation, or skin injuries.
SYMPTOMS AND SIGNS:

MELANIN IS UNEVENLY DISTRIBUTED DUE TO DIFFERENT TRIGGER FACTORS

COMMON TREATMENTS:

Taking care of your skin through proper skincare, sun protection, and regular visits to a dermatologist is crucial for maintaining skin health and preventing various dermatological conditions, including hyperpigmentation

IMPORTANCE OF SKINCARE:


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Medical References
Signs and Symptoms / Common treatments:
Grimes, P. E. (2007). A microsponge formulation of hydroquinone 4% and retinol 0.15% in the treatment of melasma and postinflammatory hyperpigmentation. Cutis, 79(6 Suppl), 27–44.
Sarkar, R., & Arora, P. (2013). Melasma update. Indian dermatology online journal, 4(4), 298–308.
Alexis, A., & Callender, V. (2010). Racial and Ethnic Differences in Skin Aging: Implications for Treatment with Fractionated Carbon Dioxide Laser. Journal of Drugs in Dermatology, 9(10), 1161–1164.
Hexsel, D., & Hexsel, C. (2014). Efficacy of new vehicle formulations of 4% hydroquinone and 0.05% tretinoin in treating solar lentigines. Journal of Drugs in Dermatology, 13(4), 390–392.
Bagatin, E., et al. (2018). New Insights on the Management of Skin Hyperpigmentation. American Journal of Clinical Dermatology, 19(1), 1–9.
Importance of skincare:
Lim, H. W., et al. (2019). Sunscreen and Prevention of Skin Aging: A Randomized Trial. Annals of Internal Medicine, 163(12), 879–889.
Kaur, R., & Zito, P. M. (2020). Cosmetics: Skin Care and Sun Protection. Treasure Island (FL): StatPearls Publishing. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539701/
Tsai, T. F., et al. (2018). Strategies for managing hyperpigmentation: a review. Journal of Dermatological Treatment, 29(4), 370–377.
Murrell, D. F., et al. (2020). Dermatological Findings Associated with COVID-19: A Comprehensive Review. Clinical Reviews in Allergy & Immunology, 59(2), 184–192.
³ Kohli, I., & Sachdeva, S. (2016). Melasma: A comprehensive update: Part I. Journal of Cutaneous and Aesthetic Surgery, 9(1), 1–7.
⁴ Passeron, T. (2017). Melasma pathogenesis and influencing factors—An overview of the latest research. Journal of the European Academy of Dermatology and Venereology, 31(S4), 8–15.
¹ Davis, E. C., & Callender, V. D. (2010). Postinflammatory hyperpigmentation: A review of the epidemiology, clinical features, and treatment options in skin of color. Journal of Clinical and Aesthetic Dermatology, 3(7), 20–31.
² Vashi, N. A., et al. (2016). Pigmentation in African American skin decreases with skin aging. Dermatologic Surgery, 42(7), 846–852.
⁵ Bin, B. H., & Kim, D. J. (2017). Genetic and epigenetic regulation of PDZK1 expression: Impact on melanogenesis. Molecular and Cellular Toxicology, 13(3), 299–304.